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::AMBERLITE™ Cation Exchange Resins

二、AMBERLITE™
Cation exchange resins for the recovery, separation and purification of pharmaceutically active compounds

AMBERLITE™ CG50 (Type 1)

Weakly acidic cation exchange resin powder for the recovery, separation, and purification of pharmaceutically active compounds

AMBERLITE™ CG50 (Type 1) is a crosslinked methacrylic and weakly acidic cation exchange resin powder used primarily for the recovery, separation, and purification of pharmaceutically active compounds.

Used in: The recovery, separation and purification of a wide range of pharmaceutically active compounds

Advantages:

  • Powder form
  • Works with a wide range of pharmaceutically active compounds

Typical Properties
These properties are typical but do not constitute specifications.

Matrix

Macroporous crosslinked methacrylate

Functional groups

-COO-

Physical form

Dry fine powder

Ionic form as supplied

H+

Total exchange capacity

10 meq/g min

Moisture content

10% max

Particle size

Nominally 100 to 200 mesh (US Std) 75 to 150 µm

AMBERLITE™ Cobalamion

Synthetic cation exchange resin for purification of Vitamin B 12 from fermentation broths

AMBERLITE™ COBALAMION is a synthetic cation exchange resin with an unusually high exchange capacity that is designed specifically for purification of Vitamin B12 from fermentation broths.

Used in: Purification of Vitamin B12 from fermentation broths

Advantages:

  • High exchange capacity
  • Excellent mechanical and osmotic stability
  • Provides ease of regeneration

Typical Properties
These properties are typical but do not constitute specifications.

Physical form

White spherical opaque beads

Ionic form as shipped

H+

Total exchange capacity

>2.6 eq/L (H+ form)

Moisture holding capacity

60 to 70% (H+ form)

Harmonic mean size

0.45 - 0.65 mm

Uniformity coefficient

<2.0

Fines content

<0.300 mm : 8.0% max

Coarse beads

>1.180 mm : 5.0% max

Maximum reversible swelling

H+ à Na+: ~ 110%

 

 

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