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::AMBERCHROM™ Chromatography Resins
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AMBERCHROM™
CG300M
|
Chromatographic
grade resin for purification of low molecular weight compounds
AMBERCHROM™ CG300M chromatographic
grade resin is designed for use in capture, purification, and polishing steps
of downstream processing protocols of growth factors and other polypeptides,
like insulin.
Advantages:
- Ideal
for transfer of purification processes from discovery to development and
full scale production of pharmaceutical and biopharmaceutical compounds
- Combining
the purification power of silica media and the chemical stability of
polymeric chromatography resins
- Wide
range of available particle sizes of beads to address different
purification requirements
- High
mechanical stability, high resolution and selectivity provide increased
product yields, resin life time and performance
|
Matrix
|
polystyrene/divinylbenzene
adsorbent
|
|
Functional
groups
|
none
|
|
Physical
form
|
Opaque
white beads
|
|
Shipping
solvent
|
20%
ethanol
|
|
Surface
area
|
700
m2/g
|
|
Pore
size(1)
|
300
Å
|
|
Mean
diameter
|
S
grade: 35 μm, M grade: 75 μm, C grade: 120 μm
|
|
Uniformity
coefficient
|
1.7
|
|
Chemical
resistance
|
Insoluble
in dilute solutions of acids or bases and common solvents: IPA, ACN, MeOH.
|
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AMBERCHROM™
HPR10
|
10
µm monosized reversed phase polymeric chromatographic resin
AMBERCHROM™ HPR10 is a monosized
reversed phase polymeric chromatographic resin that combines superior
mechanical stability and high resolution power of silica with the selectivity
and chemical stability of a polymeric resin. This translates directly in
increased product yields, longer resin life time and higher overall
efficiency
Advantages:
- Ideal
for transfer of purification processes from discovery to development and
full scale production of pharmaceutical and biopharmaceutical compounds
- Combining
the purification power of silica media and the chemical stability of
polymeric chromatography resins
- Wide
range of available particle sizes of beads to address different
purification requirements
- High
mechanical stability, high resolution and selectivity provide increased
product yields, resin life time and performance
|
Typical Properties
These properties are typical but do not constitute
specifications.
|
|
Matrix
|
Polystyrene/divinylbenzene
|
|
Pore
size
|
300
angstroms
|
|
Particle
size
|
10
μm
|
|
pH
range
|
1
- 14
|
|
Operating
temperature
|
4
- 40 °C
|
|
Maximum
pressure
|
100
bar
|
|
Recommended
mobile phases
|
Mixtures
of ACN, EtOH, MeOH, propanol, isopropanol, and acetone
|
|
Rehydration
and packing
|
60%
n-propanol or 60% n-isopropanol in water
|
|
Chemical
resistance
|
Insoluble
in dilute solutions of acides or bases and common solvents: IPA, ACN, MeOH,
EtOH.
|
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AMBERCHROM™ XT20
|
Polymeric
resin for chromatographic purification of pharmaceuticals and
biopharmaceuticals
AMBERCHROM™ XT20 is a highly
efficient, pH-stable chromatographic grade resin for use in reversed phase
chromatography. In particular it is used in the purification of
pharmaceuticals and biopharmaceuticals, like small proteins and peptides
Advantages:
- Ideal
for transfer of purification processes from discovery to development and
full scale production of pharmaceutical and biopharmaceutical compounds
- Combining
the purification power of silica media and the chemical stability of
polymeric chromatography resins
- Wide
range of available particle sizes of beads to address different
purification requirements
- High
mechanical stability, high resolution and selectivity provide increased
product yields, resin life time and performance
|
Table 2: Typical Properties
These properties are typical but do not constitute
specifications.
|
|
Matrix
|
Polystyrene
divinylbenzene
|
|
Pore
size
|
300
Å
|
|
Particle
size
|
AMBERCHROM
XT20: 20 µm
AMBERCHROM XT30: 30 µm
|
|
pH
range
|
1
- 14
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|
Operating
temperature
|
4
- 40°C
|
|
Maximum
pressure
|
60
bar
|
|
Recommended
mobile phases
|
Mixtures
of ACN, EtOH, MeOH, propanol, isopropanol and acetone
|
|
Rehydration
and packing
|
60%
n-propanol or 60% n-isopropanol in water
|
|
Chemical
Resistance
|
Insoluble
in dilute solutions of acids or bases and common solvents:IPA, ACN, MeOH,
EtOH
|
|
|
AMBERCHROM™ XT30
|
Reversed
phase chromatographic grade resin for biomolecule purification and polishing
with a particle size range of 30 microns
AMBERCHROM™ XT30 is a polystyrene
divinylbenzene polishing grade resin manufactured for high value reversed
phase chromatographic applications, and ideally suited for the separation of
proteins, peptides, and nucleic acids.
Advantages:
- Ideal
for transfer of purification processes from discovery to development and
full scale production of pharmaceutical and biopharmaceutical compounds
- Combining
the purification power of silica media and the chemical stability of
polymeric chromatography resins
- Wide
range of available particle sizes of beads to address different
purification requirements
- High
mechanical stability, high resolution and selectivity provide increased
product yields, resin life time and performance
|
Typical Properties
These properties are typical but do not constitute
specifications.
|
|
Matrix
|
Polystyrene
divinylbenzene
|
|
Pore
size
|
300Å
|
|
Particle
size
|
30
µm
|
|
pH
range
|
1
- 14
|
|
Operating
temperature
|
4
- 40°C
|
|
Maximum
pressure
|
60
bar
|
|
Recommended
mobile phases
|
Mixtures
of ACN, EtOH, MeOH, propanol, isopropanol and acetone
|
|
Rehydration
and packing
|
60%
n-propanol or 60% n-isopropanol in water
|
|
Chemical
resistance
|
Insoluble
in dilute solutions of acids or bases and common solvents: IPA, ACN, MeOH, EtOH
|
|
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AMBERCHROM™ CG161C
|
Chromatographic
grade, coarse-bead size resin suitable for adsorption and reversed phase
liquid chromatography
AMBERCHROM™ CG161C is a macroporous
polymeric resin suitable for high resolution, low pressure chromatography and
characterized by a high capacity for a variety of pharmaceutical compounds.
Advantages:
- Ideal
for transfer of purification processes from discovery to development and
full scale production of pharmaceutical and biopharmaceutical compounds
- Combining
the purification power of silica media and the chemical stability of
polymeric chromatography resins
- Wide
range of available particle sizes of beads to address different
purification requirements
- High
mechanical stability, high resolution and selectivity provide increased
product yields, resin life time and performance
|
Typical
Physical Properties
These properties are typical but do not constitute
specifications.
|
|
Matrix
|
Polystyrene/Divinylbenzene
macroreticular adsorbent
|
|
Functional
Groups
|
None
|
|
Physical
Form
|
Opaque
white beads
|
|
Shipping
Solvent
|
20%
ethanol
|
|
Surface
Area
|
900
m2/g
|
|
Pore
Size
|
150
Å
|
|
Mean
Diameter
|
S
grade: 35 microns
M grade: 75 microns
C grade: 120 microns
|
|
Uniformity
Coefficient
|
1.7
|
|
Chemical
Resistance
|
Insoluble
in dilute solutions of acids or bases and common solvents: IPA, ACN, MeOH.
|
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AMBERCHROM™
CG71C
|
Polymeric
coarse-bead size resin for use in chromatographic purification and a variety
of pharmaceutical applications
AMBERCHROM™ CG71C is an insoluble
aliphatic (acrylic ester) polymer ideal for high value chromatographic
applications, offering a high surface area and unique pore size and pore
volume distribution.
Advantages:
- Ideal
for transfer of purification processes from discovery to development and
full scale production of pharmaceutical and biopharmaceutical compounds
- Combining
the purification power of silica media and the chemical stability of
polymeric chromatography resins
- Wide
range of available particle sizes of beads to address different
purification requirements
- High
mechanical stability, high resolution and selectivity provide increased
product yields, resin life time and performance
|
Typical
Physical Properties
These properties are typical but do not constitute
specifications.
|
|
Matrix
|
Acrylic
ester macroreticular adsorbent
|
|
Functional
groups
|
None
|
|
Physical
form
|
Opaque
white beads
|
|
Shipping
solvent
|
20%
ethanol
|
|
Surface
area
|
500
m2/g
|
|
Pore
size
|
250
Å
|
|
Mean
diameter
|
S
grade: 35 microns
M grade: 75 microns
C grade: 120 microns
|
|
Uniformity
coefficient
|
1.7
|
|
Chemical
resistance
|
Insoluble
in dilute solutions of acids or bases and common solvents: IPA, ACN, MeOH.
|
|
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AMBERCHROM™
CG71S
|
Polymeric,
small-bead size resin for use in chromatographic purification and a variety
of pharmaceutical applications
AMBERCHROM™ CG71S is an insoluble
aliphatic (acrylic ester) polymer ideal for high value chromatographic
applications, offering a high surface area and unique pore size and pore
volume distribution.
Advantages:
- Ideal
for transfer of purification processes from discovery to development and
full scale production of pharmaceutical and biopharmaceutical compounds
- Combining
the purification power of silica media and the chemical stability of
polymeric chromatography resins
- Wide
range of available particle sizes of beads to address different
purification requirements
- High
mechanical stability, high resolution and selectivity provide increased
product yields, resin life time and performance
|
Typical Properties
These properties are typical but do not constitute
specifications.
|
|
Matrix
|
Acrylic
ester macroreticular adsorbent
|
|
Functional
groups
|
None
|
|
Physical
Form
|
Opaque
white beads
|
|
Shipping
solvent
|
20%
ethanol
|
|
Surface
area
|
500
m2/g
|
|
Pore
size
|
250
Å
|
|
Mean
diameter
|
S
grade: 35 microns
M grade: 75 microns
C grade: 120 microns
|
|
Uniformity
coefficient
|
1.7
|
|
Chemical
resistance
|
Insoluble
in dilute solutions of acids or bases and common solvents: IPA, ACN, MeOH.
|
|
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AMBERCHROM™
CG1000S
|
Chromatographic
grade resin suitable for adsorption and reversed phase liquid chromatography
AMBERCHROM™ CG1000S is an insoluble
polystyrene divinylbenzene polymer suitable for high resolution, low pressure
chromatography and characterized by a high capacity for a variety of
pharmaceutical compounds.
Advantages:
- Ideal
for transfer of purification processes from discovery to development and
full scale production of pharmaceutical and biopharmaceutical compounds
- Combining
the purification power of silica media and the chemical stability of
polymeric chromatography resins
- Wide
range of available particle sizes of beads to address different
purification requirements
- High
mechanical stability, high resolution and selectivity provide increased
product yields, resin life time and performance
|
Typical
Physical Properties
These properties are typical but do not constitute
specifications.
|
|
Matrix
|
Polystyrene/Divinylbenzene
adsorbent
|
|
Functional
groups
|
None
|
|
Physical
form
|
Opaque
white beads
|
|
Shipping
solvent
|
20%
ethanol
|
|
Surface
area
|
200
m2/g
|
|
Pore
size[1]
|
1000
Å
|
|
Mean
diameter
|
S
grade: 35 microns
|
|
Uniformity
coefficient
|
1.7
|
|
Chemical
resistance
|
Insoluble
in dilute solutions of acids or bases and common solvents: IPA, ACN, MeOH.
|
|
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AMBERCHROM™
CG161S
|
Chromatographic
grade, small-bead size resin suitable for adsorption and reversed phase liquid
chromatography
AMBERCHROM™ CG161S is a macroporous
polymeric resin suitable for high resolution, low pressure chromatography and
characterized by a high capacity for a variety of pharmaceutical compounds.
Advantages:
- Ideal
for transfer of purification processes from discovery to development and
full scale production of pharmaceutical and biopharmaceutical compounds
- Combining
the purification power of silica media and the chemical stability of
polymeric chromatography resins
- Wide
range of available particle sizes of beads to address different
purification requirements
- High
mechanical stability, high resolution and selectivity provide increased
product yields, resin life time and performance
|
Typical
Physical Properties
These properties are typical but do not constitute
specifications.
|
|
Matrix
|
Polystyrene/Divinylbenzene
macroreticular adsorbent
|
|
Functional
groups
|
None
|
|
Physical
form
|
Opaque
white beads
|
|
Shipping
solvent
|
20%
ethanol
|
|
Surface
area
|
900
m2/g
|
|
Pore
size[1]
|
150
Å
|
|
Mean
diameter
|
S
grade: 35 microns
M grade: 75 microns
C grade: 120 microns
|
|
Uniformity
coefficient
|
1.7
|
|
Chemical
resistance
|
Insoluble
in dilute solutions of acids or bases and common solvents: IPA, ACN, MeOH.
|
|
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AMBERCHROM™
CG300C
|
Insoluble
polystyrene divinylbenzene polymer for high value chromatographic
applications
AMBERCHROM™ CG300C is a
chromatographic grade resin suitable for use in many pharmaceutical
applications in the front end capture, purification, and desalting modes of
operation.
Advantages:
- Ideal
for transfer of purification processes from discovery to development and
full scale production of pharmaceutical and biopharmaceutical compounds
- Combining
the purification power of silica media and the chemical stability of
polymeric chromatography resins
- Wide
range of available particle sizes of beads to address different
purification requirements
- High
mechanical stability, high resolution and selectivity provide increased
product yields, resin life time and performance
|
Typical Physical Properties
These properties are typical but do not constitute
specifications.
|
|
Matrix
|
Polystyrene/divinylbenzene
adsorbent
|
|
Functional
Groups
|
None
|
|
Physical
form
|
Opaque
white beads
|
|
Shipping
solvent
|
20%
ethanol
|
|
Surface
area
|
700
m2/g
|
|
Pore
size[1]
|
300
Å
|
|
Mean
Diameter
|
S
grade: 35 microns
M grade: 75 microns
C grade: 120 microns
|
|
Uniformity
coefficient
|
1.7
|
|
Chemical
resistance
|
Insoluble
in dilute solutions of acids or bases and common solvents:IPA, ACN, MeOH.
|
|
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AMBERCHROM™
CG71M
|
Polymeric,
medium-bead size resin for use in chromatographic purification and a variety
of pharmaceutical applications
AMBERCHROM™ CG71M is an insoluble
aliphatic (acrylic ester) polymer ideal for high value chromatographic
applications, offering a high surface area and unique pore size and pore
volume distribution.
Advantages:
- Ideal
for transfer of purification processes from discovery to development and
full scale production of pharmaceutical and biopharmaceutical compounds
- Combining
the purification power of silica media and the chemical stability of
polymeric chromatography resins
- Wide
range of available particle sizes of beads to address different
purification requirements
- High
mechanical stability, high resolution and selectivity provide increased
product yields, resin life time and performance
|
Typical
Physical Properties
These properties are typical but do not constitute
specifications.
|
|
Matrix
|
Acrylic
ester macroreticular adsorbent
|
|
Functional
groups
|
None
|
|
Physical
form
|
Opaque
white beads
|
|
Shipping
solvent
|
20%
ethanol
|
|
Surface
area
|
500
m2/g
|
|
Pore
size[1]
|
250
Å
|
|
Mean
diameter
|
S
grade: 35 microns
M grade: 75 microns
C grade: 120 microns
|
|
Uniformity
coefficient
|
1.7
|
|
Chemical
resistance
|
Insoluble
in dilute solutions of acids or bases and common solvents: IPA, ACN, MeOH.
|
|
|
AMBERCHROM™
CG161M
|
Chromatographic
grade, medium-bead size resin suitable for adsorption and reversed phase liquid
chromatography
AMBERCHROM CG161M is a macroporous
polymeric resin suitable for high resolution, low pressure chromatography and
characterized by a high capacity for a variety of pharmaceutical compounds.
Advantages:
- Ideal
for transfer of purification processes from discovery to development and
full scale production of pharmaceutical and biopharmaceutical compounds
- Combining
the purification power of silica media and the chemical stability of
polymeric chromatography resins
- Wide
range of available particle sizes of beads to address different
purification requirements
- High
mechanical stability, high resolution and selectivity provide increased
product yields, resin life time and performance
|
Typical
Physical Properties
These properties are typical but do not constitute
specifications.
|
|
Matrix
|
Polystyrene/Divinylbenzene
macroreticular adsorbent
|
|
Functional
groups
|
None
|
|
Physical
form
|
Opaque
white beads
|
|
Shipping
solvent
|
20%
ethanol
|
|
Surface
area
|
900
m²/g
|
|
Pore
size[1]
|
150
Å
|
|
Mean
diameter
|
S
grade: 35 microns
M grade: 75 microns
C grade: 120 microns
|
|
Uniformity
coefficient
|
1.7
|
|
Chemical
resistance
|
Insoluble
in dilute solutions of acids or bases and common solvents: IPA, ACN, MeOH.
|
|
|
|
|
|
|
|
|